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Sickle cell disease affects your mind and body

Call the NAMI Helpline at 800-950-6264 or text “NAMI” to 62640
Studies show a significant relationship between physical pain and symptoms of depression and anxiety, as both disorders share pathways within the brain.
Sickle cell disease changes how you feel and function in many ways
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Because the crescent shape of sickle cells makes them stiff and sticky, they can stick together and block blood flow.

People with sickle cell disease experience tissue injury, impaired oxygen supply and inflammation throughout their body

This leads to:

  • pain
  • fatigue
  • other difficulties, including in the brain and central nervous system
Tanzania and Mario, individuals living with sickle cell disease
The brain is part of the central nervous system, which interacts with the rest of your body. The limbic system is the part of your brain that feels touch or pain. It also helps in regulating emotions, including responses like anxiety or depression, and how you respond to stress – this is why pain is a physical as well as emotional experience. Think of the physical pain you might feel during grief or significant disappointment – the term ‘heartbreak’ vividly describes how someone might feel emotional and physical pain at the same time.
Uncontrolled stress can create anxiety, leading to the release of adrenaline, which can tighten blood vessels and increase your heart rate, potentially worsening pain and other symptoms.
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Chronic pain, fatigue, and frequently feeling down can sometimes make you feel emotionally exhausted and even hopeless. This in turn can make it difficult to stick with treatment plans, routine self-care – or even reach out to someone for support.
Visit NAMI to learn more about mental health, treatment options, coping strategies, treatment providers and more.
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Expand your plan
Having a plan to address symptoms and improve your health in the long-term is another way to feel more in control and boost your mental wellness.
Strengthening your health preventatively and effectively managing stress, as well as having coping strategies for a crisis, are key parts to successfully managing sickle cell disease and your mental health.
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Expand your plan
Having a plan to address symptoms and improve your health in the long-term is another way to feel more in control and boost your mental wellness.
Strengthening your health preventatively and effectively managing stress, as well as having coping strategies for a crisis, are key parts to successfully managing sickle cell disease and your mental health.
Proactive health efforts and managing stress are linked together in a variety of ways that are vital to maintaining blood pressure, controlling pain, and improving symptoms of anxiety or depression. For example, everyday lifestyle factors have a major impact on both physical and mental health.

Generations have understood instinctively that food is medicine.

In fact, the potential of combining natural and pharmaceutical medicine is a part of a growing approach to the management of sickle cell disease in Africa. Many traditional foods and herbs are incorporated and studied in combination with medical treatment.

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Nutrition

The cells in your gut play a key role in health. The microbes within the stomach and digestive tract spur metabolism, brain and mental health, energy, the immune system, and many other complex processes. Foods that we eat interact with the gut cells and affect all of these areas, notably inflammation, which can cause symptoms to flare, including mood symptoms like depression and anxiety.

One way to help reduce inflammation is to include foods in your diet that help lower it, such as omega-3 fatty acids.

  • Salmon and other fatty fish, edamame, walnuts, flaxseed, eggs and dairy are all good sources.

Other foods that help reduce inflammation include:

  • Leafy green vegetables, berries, oranges and tomatoes, brown rice, beans and mushrooms.
  • Probiotic foods are also important, like yogurt, cottage cheese, sauerkraut, pickles and pickled vegetables.

Healthy foods are important to mental health. As another example, brain chemicals such as serotonin are produced in the gut and thus need healthy food sources. Over the years, the amount of research on the connection of food and mental health has become so extensive that the specialty known as nutritional psychiatry was developed.

As you expand on your plan for symptom management, creating a meal plan that incorporates whole and minimally processed foods can be a powerful tool. If you’re unsure where to begin, you can start by replacing foods gradually and setting small goals to build on.

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Water is life

Any mention of nutrition in sickle cell disease must include the importance of hydration. Hydration is vital to aiding the prevention of red blood cell sickling and for keeping blood from becoming too thick. The benefits of drinking plenty of water are extensive – it can help you feel fuller, aids in digestion, and helps carry nutrients and medications throughout the body more effectively.

Just as importantly, adequate water intake improves brain function, fatigue and mood, while inadequate hydration raises the risk of symptoms of anxiety and depression.

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If you don’t enjoy plain water, you can infuse it with fruit, an ounce of fruit juice, sliced cucumber or mint. Consider freezing fruit or fruit juice and using it as an ice cube.

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Physical Activity

The benefits of exercise for mental health are well documented. While sickle cell disease requires caution for some, recent research indicates that light exercise such as walking, biking, stretching and strength training can improve circulation and symptoms.

It’s important to talk to your doctor first, but physical activity reduces stress, lowers blood pressure, and improves brain function, memory and mood.

As with any changes you make, set small, buildable goals.
A little physical movement is better than none.
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Focus on progress. Perfection is not necessary.
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Enlist a friend to join you and help each other stay motivated.
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Enjoy the benefits of better mental health.